PGT by NGS offers clarity, confidence, and improved outcomes in IVF treatment. By selecting genetically healthy embryos, you take a significant step toward achieving a successful pregnancy.
Preimplantation Genetic Testing (PGT) using Next-Generation Sequencing (NGS) is an advanced technique used during IVF to analyze the genetic health of embryos before transfer. It helps identify chromosomal abnormalities and inherited genetic conditions, allowing the selection of the healthiest embryos for implantation.
At Bangkok Central Clinic, we use cutting-edge NGS technology to deliver highly accurate genetic insights, improving IVF success rates and reducing the risk of miscarriage or genetic disorders.
PGT is an advanced genetic testing technique performed on embryos created through IVF. Using cutting-edge Next-Generation Sequencing (NGS) technology, it allows comprehensive analysis of all 23 pairs of chromosomes with exceptional precision. This helps detect abnormalities such as extra or missing chromosomes (aneuploidy), gene mutations, and structural rearrangements.
By identifying genetically normal embryos, PGT enables specialists to select those with the highest potential for successful implantation and a healthy pregnancy. This not only improves IVF success rates but also reduces the risk of miscarriage and genetic disorders.
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
PGT-A is an advanced genetic screening technique used during IVF to evaluate embryos for chromosomal abnormalities before implantation. These abnormalities—such as extra or missing chromosomes (aneuploidy)—are one of the leading causes of failed implantation, recurrent miscarriages, and genetic conditions like Down syndrome.
During the IVF process, a few cells are carefully biopsied from the developing embryo and analyzed in a specialized laboratory. This allows doctors to identify which embryos have the correct number of chromosomes (euploid embryos) and are more likely to result in a healthy pregnancy.
By selecting chromosomally normal embryos for transfer, PGT-A helps improve implantation rates, reduce the risk of miscarriage, and enhance the overall success rates of IVF. It also supports better decision-making for patients, especially those with a history of repeated IVF failures, miscarriages, or advanced maternal age.
PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)
PGT-M is recommended for individuals or couples with a known history of inherited genetic disorders. This test identifies specific gene mutations and ensures that only unaffected embryos are selected for transfer.
It is commonly used for conditions such as thalassemia, cystic fibrosis, and other inherited diseases.
PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
PGT-SR is designed for individuals with chromosomal structural abnormalities, such as translocations or inversions. These conditions may not affect overall health but can impact fertility and increase the risk of miscarriage.
PGT-SR helps identify embryos with balanced chromosome structures, improving the chances of a healthy pregnancy.
Choosing the Right PGT Option
The most suitable PGT test depends on your medical history, genetic background, and fertility goals. Our specialists will guide you in selecting the right approach to maximize your chances of success while ensuring the safety and health of your future child.
The PGT testing process is carefully managed by experienced embryologists and fertility specialists:
Eggs are retrieved from the ovaries and fertilized with sperm in a controlled laboratory environment to create embryos.
The fertilized eggs are carefully monitored as they grow and develop into embryos over 5–6 days, reaching the blastocyst stage.
At the blastocyst stage, a few cells are gently and safely removed from the outer layer of the embryo. This process does not harm the embryo’s development.
The sampled cells are analyzed using advanced Next-Generation Sequencing (NGS) technology for PGT-A/PGT-M, allowing accurate assessment of chromosome number and detection of genetic abnormalities.
Based on the test results, embryos with the correct number of chromosomes (genetically normal embryos) are identified and selected for transfer.
A healthy embryo is then transferred into the uterus, increasing the chances of successful implantation and a healthy pregnancy.
The cost of PGT by NGS varies depending on individual treatment plans and clinical requirements.
Factors that influence cost include:
What’s included in our PGT package:
We offer transparent pricing and comprehensive packages to help you plan your treatment with confidence.
Success with PGT depends on multiple factors:
At Bangkok Central Clinic, we combine state-of-the-art technology with an experienced fertility team to deliver outcomes comparable to leading international fertility centers, ensuring patients receive the highest standard of care throughout their journey.
PGT (Preimplantation Genetic Testing) is used during IVF to screen embryos for genetic abnormalities before transfer. It helps select the healthiest embryos, improving the chances of a successful pregnancy and reducing the risk of miscarriage or genetic disorders.
PGT-A checks for chromosomal abnormalities, PGT-M tests for specific inherited genetic diseases, and PGT-SR is used for structural chromosome issues like translocations. The right test depends on your medical and family history.
PGT is recommended for couples with a history of genetic disorders, recurrent miscarriages, failed IVF cycles, or advanced maternal age. It is also useful for those who want to increase and improves their chances of a healthy pregnancy and family balancing.
PGT improves & increase the chances of success by selecting genetically healthy embryos and reducing the risk of implantation failure or miscarriage.
Embryo biopsy is a safe and commonly used procedure when performed by experienced embryologists. Only a few cells are removed from the embryo, and this does not affect its ability to develop normally.
PGT by NGS offers clarity, confidence, and improved outcomes in IVF treatment. By selecting genetically healthy embryos, you take a significant step toward achieving a successful pregnancy.
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